The findings documented here are interesting and valuable with respect to revealing genetic players that may underlie AD. However, there are concerns related to the analysis pipeline and the basic ...

This important study identifies and characterizes a set of amino acid states that can rescue protein function in the presence of substantially deleterious mutations. Some of these super-compensatory ...

Overall, these in vitro experiments demonstrate that pharmacological activation of TRPML1 stimulates AMPK via a Ca 2+ -CaMKKβ-dependent pathway, thereby promoting GLUT4 translocation to the PM. This ...

Here, we investigated the role of the Chikungunya virus (CHIKV) nsP3 macrodomain catalytic activity by mutating the active-site asparagine 24 (N24). N24 mutant viruses rapidly selected for ...

Humans make thousands of decisions under ambiguity every day, where most times the probabilities of getting beneficial outcomes are not fully known. Although ambiguity aversion is well characterized ...

Foveal attentional processing coordinates with peripheral attention to dynamically shape global attention allocation and fixation behavior during active vision.

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We are publishing this correction to address a transcription error in the reported catalog number for the p16 antibody used in our study. During manuscript ...